Study Description
The main purpose of this study is to assess preliminary efficacy and safety of CFZ533,
LYS006, MAS825 , LOU064 and VAY736 in patients with moderate to severe hidradenitis
suppurativa and to determine if CFZ533, LYS006, MAS825, LOU064 and VAY736 have an
adequate clinical profile for further clinical development.
Interventions
CFZ533
LOU064 100mg
LOU064 25mg
LYS006
MAS825
Placebo to CFZ533
Placebo to LOU064
Placebo to LYS006
Placebo to MAS825
Placebo to VAY736
VAY736
Eligibility Criteria
Inclusion Criteria:
- Patients with moderate to severe HS based on the number of lesions, fistulae and
anatomical areas involved
- Minimal body weight of 50 kg
- Able to communicate well with the investigator and understand and comply with the
requirements of the study, and the ability and willingness to conduct study visits
as per the study schedule
Exclusion Criteria:
- Use of other investigational drugs at the time of screening or before
- Women physiologically capable of becoming pregnant, unless they are using highly
effective methods of contraception
- Pregnant or lactating women
Other protocol-defined inclusion/exclusion criteria may apply
Novartis Investigative Site
Recruiting
Graz,8036,Austria
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Bruxelles,1070,Belgium
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Marseille,13885,France
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Nice,06202,France
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Reims,51100,France
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Rouen,76031,France
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Antony,92160,France
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Lyon,69437,France
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Recruiting
Hamburg,20246,Germany
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Recruiting
Bochum,44791,Germany
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Recruiting
Frankfurt,60590,Germany
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Recruiting
Valencia,46026,Spain
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Recruiting
Granada,Andalucia,18014,Spain
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Sabadell,Barcelona,08208,Spain
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Recruiting
Manises,Valencia,46940,Spain
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Barcelona,08041,Spain
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Las Palmas de Gran Canaria,35010,Spain
Novartis Investigative Site
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Madrid,28031,Spain
Medical University of South Carolina MUSC .
Recruiting
Charleston,South Carolina,29425,United States
Lara Wine Lee
University of South Florida
Recruiting
Tampa,Florida,33612,United States
Lilia Correa
NorthShore University Health System North Shore
Recruiting
Skokie,Illinois,60077,United States
Stephanie Mehlis
Olympian Clinical Research .
Recruiting
Clearwater,Florida,33756,United States
Ingrid Rodriguez
Matthew Zook
Dawes Fretzin Clinical Rea Group
Recruiting
Indianapolis,Indiana,46250,United States
Kenneth Dawes
Worldwide Contacts
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